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Scientists Discover Persistent Genome Loops During Cell Division, Challenging Long-Held Beliefs

A groundbreaking MIT study reveals that tiny 3D loops in the genome persist during cell division, challenging decades of scientific understanding. These microcompartments appear to strengthen as chromosomes compact, potentially helping cells maintain genetic memory across divisions.

Redefining Cellular Division

In a discovery that challenges fundamental biological understanding, researchers at MIT have found that tiny three-dimensional loops within the genome persist during cell division, according to a new study published in Nature Structural & Molecular Biology. This finding contradicts the long-standing belief that the genome loses all its complex internal structure during mitosis, with scientists previously thinking the process represented a complete reset of genomic architecture.